Amniotic fluid stem cell‐derived extracellular vesicles educate type 2 conventional dendritic cells to rescue autoimmune disorders in a multiple sclerosis mouse model

Abstract Dendritic cells (DCs) are essential orchestrators of immune responses and represent potential targets for immunomodulation in autoimmune diseases. Human amniotic fluid secretome is abundant in immunoregulatory factors, with extracellular vesicles (EVs) being a significant component. However...

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Hlavní autoři:	Giorgia Manni, Marco Gargaro, Doriana Ricciuti, Simona Fontana, Eleonora Padiglioni, Marco Cipolloni, Tommaso Mazza, Jessica Rosati, Alessandra di Veroli, Giulia Mencarelli, Benedetta Pieroni, Estevão Carlos Silva Barcelos, Giulia Scalisi, Francesco Sarnari, Alessandro di Michele, Luisa Pascucci, Francesca deFranco, Teresa Zelante, Cinzia Antognelli, Gabriele Cruciani, Vincenzo Nicola Talesa, Rita Romani, Francesca Fallarino
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2024-06-01
Edice:	Journal of Extracellular Vesicles
Témata:	amniotic fluid stem cells autoimmune diseases conventional dendritic cell type 2 (cDC2) dendritic cells experimental autoimmune encephalomyelitis (EAE) extracellular vesicles
On-line přístup:	https://doi.org/10.1002/jev2.12446
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