A Novel Bacterium-Like Particle Vaccine Displaying the MERS-CoV Receptor-Binding Domain Induces Specific Mucosal and Systemic Immune Responses in Mice

Middle East respiratory syndrome coronavirus (MERS-CoV), a new coronavirus that has been causing severe and fatal acute respiratory illnesses in humans since its outbreak in 2012, has raised public fear worldwide. The development of prophylactics and therapeutics is urgently needed to prevent and co...

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Hlavní autoři:	Entao Li, Hang Chi, Pei Huang, Feihu Yan, Ying Zhang, Chuanyu Liu, Zhenshan Wang, Guohua Li, Shengnan Zhang, Ruo Mo, Hongli Jin, Hualei Wang, Na Feng, Jianzhong Wang, Yuhai Bi, Tiecheng Wang, Weiyang Sun, Yuwei Gao, Yongkun Zhao, Songtao Yang, Xianzhu Xia
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	MDPI AG 2019-08-01
Edice:	Viruses
Témata:	MERS-CoV subunit vaccine bacterium-like particles intranasal administration mucosal immune
On-line přístup:	https://www.mdpi.com/1999-4915/11/9/799
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