Wnt signaling regulates the lineage differentiation potential of mouse embryonic stem cells through Tcf3 down-regulation.

Canonical Wnt signaling plays a rate-limiting role in regulating self-renewal and differentiation in mouse embryonic stem cells (ESCs). We have previously shown that mutation in the Apc (adenomatous polyposis coli) tumor suppressor gene constitutively activates Wnt signaling in ESCs and inhibits the...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Yaser Atlasi, Rubina Noori, Claudia Gaspar, Patrick Franken, Andrea Sacchetti, Haleh Rafati, Tokameh Mahmoudi, Charles Decraene, George A Calin, Bradley J Merrill, Riccardo Fodde
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Public Library of Science (PLoS) 2013-05-01
Colecção:	PLoS Genetics
Acesso em linha:	https://doi.org/10.1371/journal.pgen.1003424
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!