Genetic Analysis Reveals Differences in CD8⁺ T Cell Epitope Regions That May Impact Cross-Reactivity of Vaccine-Induced T Cells against Wild-Type Mumps Viruses

Nowadays, mumps is re-emerging in highly vaccinated populations. Waning of vaccine-induced immunity plays a role, but antigenic differences between vaccine and mumps outbreak strains could also contribute to reduced vaccine effectiveness. CD8⁺ T cells play a critical role in immunity to v...

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Principais autores:	Patricia Kaaijk, Maarten E. Emmelot, Jeroen Kerkhof, Cécile A.C.M. van Els, Hugo D. Meiring, Jelle de Wit, Rogier Bodewes
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2021-06-01
Series:	Vaccines
Assuntos:	T cell epitopes T cell response cytotoxic CD8<sup>+</sup> T cells mumps virus Jeryl–Lynn mumps vaccine wild-type strains
Acceso en liña:	https://www.mdpi.com/2076-393X/9/7/699
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