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Missing regulatory effects on complex traits: Contribution of distal variants

Most genetic effects on complex traits lie in non-coding regions, yet many show no regulatory activity in standard gene expression assays. In this issue of Cell Genomics, Arthur et al.1 add early development-like cell types and chromatin assays, showing that distal variants missed in expression assa...

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Bibliografische gegevens
Hoofdauteurs: Sool Lee, Hakhamanesh Mostafavi
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2025-03-01
Reeks:Cell Genomics
Online toegang:http://www.sciencedirect.com/science/article/pii/S2666979X25000655
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