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Two novel human NUMB isoforms provide a potential link between development and cancer

<p>Abstract</p> <p>We previously identified four functionally distinct human NUMB isoforms. Here, we report the identification of two additional isoforms and propose a link between the expression of these isoforms and cancer. These novel isoforms, NUMB5 and NUMB6, lack exon 10 and are expressed in c...

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Autori principali: Prudovsky Igor, Adams Tamara L, Cowling Rebecca, Kubu Chris, Tremblay Roger, Bani-Yaghoub Mahmud, Karaczyn Aldona, Spicer Douglas, Friesel Robert, Vary Calvin, Verdi Joseph M
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2010-12-01
Serie:Neural Development
Accesso online:http://www.neuraldevelopment.com/content/5/1/31
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