Interferon-gamma driven elevation of CXCL9: a new sepsis endotype independently associated with mortalityResearch in context

Summary: Background: Endotype classification becomes the cornerstone of understanding sepsis pathogenesis. Macrophage activation-like syndrome (MALS) and immunoparalysis are the best recognized major endotypes, so far. Interferon-gamma (IFNγ) action on tissue macrophages stimulates the release of t...

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Detalhes bibliográficos

Principais autores:	Evangelos J. Giamarellos-Bourboulis, Massimo Antonelli, Frank Bloos, Ioanna Kotsamidi, Christos Psarrakis, Konstantina Dakou, Daniel Thomas-Rüddel, Luca Montini, Josef Briegel, Georgia Damoraki, Panagiotis Koufargyris, Souzana Anisoglou, Eleni Antoniadou, Glykeria Vlachogianni, Christos Tsiantas, Matteo Masullo, Aikaterini Ioakeimidou, Eumorfia Kondili, Maria Ntaganou, Eleni Gkeka, Vassileios Papaioannou, Effie Polyzogopoulou, Armin J. Reininger, Gennaro De Pascale, Michael Kiehntopf, Eleni Mouloudi, Michael Bauer
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-11-01
Colecção:	EBioMedicine
Assuntos:	Sepsis Interferon-gamma CXCL9 Macrophages Outcome
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S235239642400450X
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