Process Analytical Technology Obtained Metastable Zone Width, Nucleation Rate and Solubility of Paracetamol in Isopropanol—Theoretical Analysis

<b>Background:</b> Metastable zone width (MSZW) and solubility are crucial for developing crystallization procedures in the purification of active pharmaceutical ingredients (APIs). Traditionally, determining these properties involves labor-intensive methods that can take weeks or even months. With...

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Auteurs principaux:	Mahmoud Ranjbar, Mayank Vashishtha, Gavin Walker, K. Vasanth Kumar
Format:	Artigo
Langue:	Inglês
Publié:	MDPI AG 2025-02-01
Collection:	Pharmaceuticals
Sujets:	crystallization kinetics metastable zone width PAT thermodynamics nucleation
Accès en ligne:	https://www.mdpi.com/1424-8247/18/3/314
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