Mechanistic analyses in kidney transplant recipients prospectively randomized to two steroid free regimen-Low dose Tacrolimus with Everolimus versus standard dose Tacrolimus with Mycophenolate Mofetil.

Calcineurin inhibitors (CNI), the cornerstone of immunosuppression after transplantation are implicated in nephrotoxicity and allograft dysfunction. We hypothesized that combined low doses of CNI and Everolimus (EVR) may result in better graft outcomes and greater tolerogenic milieu. Forty adult ren...

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Autori principali:	Opas Traitanon, James M Mathew, Aneesha Shetty, Sai Vineela Bontha, Daniel G Maluf, Yvonne El Kassis, Sook H Park, Jing Han, M Javeed Ansari, Joseph R Leventhal, Valeria Mas, Lorenzo Gallon
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Public Library of Science (PLoS) 2019-01-01
Serie:	PLoS ONE
Accesso online:	https://doi.org/10.1371/journal.pone.0216300
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