Synthesis and computational insights of hybrid heterocyclic bis-chalcone compounds and their cytotoxic effects against breast cancer cells

Breast cancer is a common disease that employs chemotherapeutic drugs as a treatment approach. However, these drugs have several adverse effects, prompting the development of new drugs. Hence, this study aimed to synthesize a series of hybrid heterocyclic bis-chalcone compounds using the Claisen-Sch...

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Autores principales:	Sadiq Abubakar, Melati Khairuddean, Noor Zafirah Ismail, Salizawati Mohamad Salhimi, Mohammad Al-Amin, Tutik Dwi Wahyuningsih
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Elsevier 2024-01-01
Colección:	Results in Chemistry
Materias:	Cytotoxicity Computational analysis Estrogen alpha receptor Bis-chalcone ADME properties
Acceso en línea:	http://www.sciencedirect.com/science/article/pii/S2211715624001607
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