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Bone Marrow Endosteal Mesenchymal Progenitors Depend on HIF Factors for Maintenance and Regulation of Hematopoiesis

Maintenance and differentiation of hematopoietic stem cells (HSCs) is regulated through cell-autonomous and non-cell-autonomous mechanisms within specialized bone marrow microenvironments. Recent evidence demonstrates that signaling by HIF-1α contributes to cell-autonomous regulation of HSC maintena...

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Principais autores: Jlenia Guarnerio, Nadia Coltella, Ugo Ala, Giovanni Tonon, Pier Paolo Pandolfi, Rosa Bernardi
格式: Artigo
语言:Inglês
出版: Elsevier 2014-06-01
丛编:Stem Cell Reports
在线阅读:http://www.sciencedirect.com/science/article/pii/S221367111400109X
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