Identification of cellular signatures associated with chinese hamster ovary cell adaptation for secretion of antibodies

The secretory capacity of Chinese hamster ovary (CHO) cells remains a fundamental bottleneck in the manufacturing of protein-based therapeutics. Unconventional biological drugs with complex structures and processing requirements are particularly problematic. Although engineered vector DNA elements c...

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Bibliografische gegevens

Hoofdauteurs:	Ying Bai, Ivan Domenech Mercadé, Ramy Elgendy, Giulia Lambiase, Sew Peak-Chew, Catarina Franco, Steven W. Wingett, Tim J. Stevens, Luigi Grassi, Noah Hitchcock, Cristina Sayago Ferreira, Diane Hatton, Elizabeth A. Miller, Rajesh K. Mistry
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Elsevier 2025-01-01
Reeks:	Computational and Structural Biotechnology Journal
Onderwerpen:	Multiomics Chinese hamster ovary cells Biotherapeutics
Online toegang:	http://www.sciencedirect.com/science/article/pii/S200103702400429X
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