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High Throughput Kinomic Profiling of Human Clear Cell Renal Cell Carcinoma Identifies Kinase Activity Dependent Molecular Subtypes.

Despite the widespread use of kinase-targeted agents in clear cell renal cell carcinoma (CC-RCC), comprehensive kinase activity evaluation (kinomic profiling) of these tumors is lacking. Thus, kinomic profiling of CC-RCC may assist in devising a classification system associated with clinical outcome...

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Principais autores: Joshua C Anderson, Christopher D Willey, Amitkumar Mehta, Karim Welaya, Dongquan Chen, Christine W Duarte, Pooja Ghatalia, Waleed Arafat, Ankit Madan, Sunil Sudarshan, Gurudatta Naik, William E Grizzle, Toni K Choueiri, Guru Sonpavde
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2015-01-01
Serier:PLoS ONE
Online adgang:http://europepmc.org/articles/PMC4583516?pdf=render
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