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Decoding the temporal dimension of innate immunity in intravesical BCG therapy

Innate immune signals encode functional instructions through temporal patterns such as oscillation frequency and duration—a principle validated at the single-cell level. Yet clinical evaluation of host responses in tumor immunotherapy remains dominated by “how strongly” the immune system is activate...

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Principais autores: Xuewen Diao, Bangwei Che, Jiancheng Zhai, Bo Shao, Kaifa Tang
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2026-07-01
Series:Frontiers in Immunology
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Acceso en liña:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1904049/full
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