Acaciasaligna extract alleviates quetiapine-induced sexual toxicity in male albino rats: Insights from UPLC-MS/MS metabolite profiling, structural and PI3K/NF-κB pathway assessments

Background: Quetiapine (QET) abuse has increased due to its anxiolytic and hedonic effects, necessitating protective adjunct treatments. Acacia saligna (A. saligna) flowers, used in traditional medicine, have potential health benefits. Aim: To investigate the protective role of A. saligna flower ext...

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Principais autores:	Shimaa Mohammad Yousof, Shaimaa A. Shehata, Ezzat A. Ismail, Samar M. Abd El-moneam, Basma S.A. Mansour, Mohamed A. Farag, Abdelsamed I. Elshamy, Abd El-Nasser G. El Gendy, Ahmed Serag, Noha M. Abd El-Fadeal, Rehab Ibrahim Abdel-Karim, Mostafa M. Mostafa, Dina H. El-Sheikh, Mohamed A. Zayed
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-07-01
Colecção:	Heliyon
Assuntos:	Acacia saligna UPLC-MS/MS Quetiapine Sexual toxicity Oxidative stress P13K/NF-κB pathway
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2405844024100242
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