Feasibility of combining JAK1 gene editing via CRISPR-CasRx with EGCG–lactoferrin nanoparticle therapy in a microneedle-based platform for atopic dermatitis

Atopic dermatitis (AD) is an inflammatory skin disease characterized by a complex pathogenesis. Current clinical treatments exhibit several limitations, including low efficacy and considerable side effects, prompting a growing interest in novel therapeutic strategies. In this study, we developed a m...

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Hlavní autoři:	Huanqing Zhu, Haonan Yu, Mengxin Huang, Panjie Sun, Yuanfang Tang, Zhanyi Zhang, Puming He, Youying Tu, Bo Li
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2026-04-01
Edice:	Materials Today Bio
Témata:	Atopic dermatitis JAK1 CRISPR-CasRx EGCG Lactoferrin Microneedle
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2590006426001274
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