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Apolipoprotein AI prevents regulatory to follicular helper T cell switching during atherosclerosis

Regulatory T (Treg) cells contribute to the anti-inflammatory response during atherogenesis. Here Gaddis et al. show that Apolipoprotein AI prevents the conversion of Treg cells into pro-atherogenic T follicular helper cells, and thus regulates the immune response during atherogenesis.

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Dettagli Bibliografici
Autori principali: Dalia E. Gaddis, Lindsey E. Padgett, Runpei Wu, Chantel McSkimming, Veronica Romines, Angela M. Taylor, Coleen A. McNamara, Mitchell Kronenberg, Shane Crotty, Michael J. Thomas, Mary G. Sorci-Thomas, Catherine C. Hedrick
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2018-03-01
Serie:Nature Communications
Accesso online:https://doi.org/10.1038/s41467-018-03493-5
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