Decoding the multifaceted interventions between human sirtuin 2 and dynamic hepatitis B viral proteins to confirm their roles in HBV replication

The human sirtuin 2 gene (SIRT2) encodes a full-length Sirt2 protein (i.e., the Sirt2 isoform 1), which primarily functions as a cytoplasmic α-tubulin deacetylase, and which promotes the growth of hepatocellular carcinoma (HCC). Hepatitis B virus (HBV) replication itself, or HBV X (HBx) protein-medi...

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Principais autores:	Zahra Zahid Piracha, Umar Saeed, Irfan Ellahi Piracha, Seneen Noor, Elyeen Noor
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2024-01-01
Serija:	Frontiers in Cellular and Infection Microbiology
Teme:	HBV replication sirtuins sirtuin 2 Sirt2.1 Sirt2.2 Sirt2.5
Online dostop:	https://www.frontiersin.org/articles/10.3389/fcimb.2023.1234903/full
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