Phlorizin ameliorates myocardial fibrosis by inhibiting pyroptosis through restraining HK1-mediated NLRP3 inflammasome activation

The specific role of phlorizin (PHL), which has antioxidant, anti-inflammatory, hypoglycemic, antiarrhythmic and antiaging effects, on myocardial fibrosis (MF) and the related pharmacological mechanisms remain unknown. The objective of this study was to determine the protective actions of PHL on iso...

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Principais autores:	Yuling Zhang, Xizhen Cheng, Yanan Wang, Haochuan Guo, Yongxing Song, Hongfang Wang, Donglai Ma
格式:	Artigo
語言:	Inglês
出版:	Elsevier 2023-11-01
叢編:	Heliyon
主題:	Myocardial fibrosis Phlorizin Pyroptosis HK1/NLRP3 signaling pathway
在線閱讀:	http://www.sciencedirect.com/science/article/pii/S2405844023084256
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