Notch signaling regulates UNC5B to suppress endothelial proliferation, migration, junction activity, and retinal plexus branching

Abstract Notch signaling guides vascular development and function by regulating diverse endothelial cell behaviors, including migration, proliferation, vascular density, endothelial junctions, and polarization in response to flow. Notch proteins form transcriptional activation complexes that regulat...

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主要な著者:	Qanber Raza, Taliha Nadeem, Seock-Won Youn, Bhairavi Swaminathan, Ahana Gupta, Timothy Sargis, Jing Du, Henar Cuervo, Anne Eichmann, Susan L. Ackerman, L. A. Naiche, Jan Kitajewski
フォーマット:	Artigo
言語:	Inglês
出版事項:	Nature Portfolio 2024-06-01
シリーズ:	Scientific Reports
主題:	Retinal angiogenesis Notch effectors UNC5B Endothelial proliferation Endothelial migration Cell–cell adhesion
オンライン･アクセス:	https://doi.org/10.1038/s41598-024-64375-z
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