Tryptophan catabolites, inflammation, and insulin resistance as determinants of chronic fatigue syndrome and affective symptoms in long COVID

Critical COVID-19 disease is accompanied by depletion of plasma tryptophan (TRY) and increases in indoleamine-dioxygenase (IDO)-stimulated production of neuroactive tryptophan catabolites (TRYCATs), including kynurenine (KYN). The TRYCAT pathway has not been studied extensively in association with t...

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Autori principali:	Hussein Kadhem Al-Hakeim, Anwar Khairi Abed, Shatha Rouf Moustafa, Abbas F. Almulla, Michael Maes
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2023-06-01
Serie:	Frontiers in Molecular Neuroscience
Soggetti:	neuro-immune neurotoxicity inflammation indoleamine-2,3-dioxygenase chronic fatigue syndrome affective symptoms
Accesso online:	https://www.frontiersin.org/articles/10.3389/fnmol.2023.1194769/full
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