Single-Cell Sequencing of Immune Cells in Human Aortic Dissection Tissue Provides Insights Into Immune Cell Heterogeneity

BackgroundInflammation plays an important role in the progression of sporadic aortic dissection (AD). Immune cells, especially macrophages, infiltrate the aorta and secrete inflammatory cytokines and matrix metalloproteinases to cause degradation of the extracellular matrix, thereby contributing to...

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Autori principali:	Yifan Liu, Lingwei Zou, Hanfei Tang, Jie Li, Hao Liu, Xiaolang Jiang, Baohong Jiang, Zhihui Dong, Weiguo Fu
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2022-03-01
Serie:	Frontiers in Cardiovascular Medicine
Soggetti:	single-cell RNA sequencing aortic dissection immune cell heterogeneity T cells macrophages leukocyte
Accesso online:	https://www.frontiersin.org/articles/10.3389/fcvm.2022.791875/full
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