Degenerating and Painful Human Intervertebral Discs Release Pronociceptive Factors and Increase Neurite Sprouting and CGRP via Nerve Growth Factor

Introduction Increasing evidence suggests that healthy and painless intervertebral discs (IVDs) are largely aneural and that degenerating and painful IVDs often are innervated. 1 Many inflammatory factors are unregulated in disc degeneration, such as interleukin (IL)-1β, IL-6, and tumor necrosis fac...

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Principais autores:	E. Krock, D. H. Rosenzweig, A. J. Chabot-Dore, P. Jarzem, M. H. Weber, J. A. Ouellet, L. S. Stone, L. Haglund
Formato:	Artigo
Idioma:	Inglês
Publicado:	SAGE Publishing 2014-05-01
Series:	Global Spine Journal
Acceso en liña:	https://doi.org/10.1055/s-0034-1376539
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