In-Silico UHPLC Method Optimization for Aglycones in the Herbal Laxatives Aloe barbadensis Mill., Cassia angustifolia Vahl Pods, Rhamnus frangula L. Bark, Rhamnus purshianus DC. Bark, and Rheum palmatum L. Roots

For the European Pharmacopoeia (Ph. Eur.) herbal monograph draft of Cassia angustifolia Vahl. and Cassia senna L. leaves and pods, a safety limitation of aloe-emodin and rhein was proposed, due to toxicological concerns. A quantitative, analytical method of the anthraquinone aglycones in all Ph. Eur...

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Detalhes bibliográficos

Principais autores:	Nadja Meier, Beat Meier, Samuel Peter, Evelyn Wolfram
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2017-10-01
Colecção:	Molecules
Assuntos:	anthraquinone aglycones aloe-emodin rhein emodin chrysophanol physcion herbal laxatives ultra high performance liquid chromatography (UHPLC) design of experiment (DOE) chromatographic modelling
Acesso em linha:	https://www.mdpi.com/1420-3049/22/11/1838
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