Peptide Centric Vβ Specific Germline Contacts Shape a Specialist T Cell Response

Certain CD8 T cell responses are particularly effective at controlling infection, as exemplified by elite control of HIV in individuals harboring HLA-B57. To understand the structural features that contribute to CD8 T cell elite control, we focused on a strongly protective CD8 T cell response direct...

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Bibliografiske detaljer

Principais autores:	Yang Wang, Alexandra Tsitsiklis, Stephanie Devoe, Wei Gao, H. Hamlet Chu, Yan Zhang, Wei Li, Wing Ki Wong, Charlotte M. Deane, David Neau, Jill E. Slansky, Paul G. Thomas, Ellen A. Robey, Shaodong Dai
Format:	Artigo
Sprog:	Inglês
Udgivet:	Frontiers Media S.A. 2022-07-01
Serier:	Frontiers in Immunology
Fag:	MHC TCR elite controller structure germline contacts
Online adgang:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.847092/full
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