Targeting KCa3.1 channels to overcome erlotinib resistance in non-small cell lung cancer cells
Abstract Almost all non-small cell lung cancer (NSCLC) patients initially responding to EGFR tyrosine kinase inhibitors (TKIs) develop acquired resistance. Since KCa3.1 channels, expressed in mitochondria and plasma membrane, regulate similar behavioral traits of NSCLC cells as EGFR, we hypothesized...
Bewaard in:
| Hoofdauteurs: | , , , , , , , , , |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2024-01-01
|
| Reeks: | Cell Death Discovery |
| Online toegang: | https://doi.org/10.1038/s41420-023-01776-5 |
| Tags: |
Geen labels, Wees de eerste die dit record labelt!
|