Widespread subcortical grey matter degeneration in primary lateral sclerosis: a multimodal imaging study with genetic profiling

Background: Primary lateral sclerosis (PLS) is a low incidence motor neuron disease which carries a markedly better prognosis than amyotrophic lateral sclerosis (ALS). Despite sporadic reports of extra-motor symptoms, PLS is widely regarded as a pure upper motor neuron disorder. The post mortem lite...

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Detalhes bibliográficos

Principais autores:	Eoin Finegan, Stacey Li Hi Shing, Rangariroyashe H. Chipika, Mark A. Doherty, Jennifer C. Hengeveld, Alice Vajda, Colette Donaghy, Niall Pender, Russell L. McLaughlin, Orla Hardiman, Peter Bede
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2019-01-01
coleção:	NeuroImage: Clinical
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S221315821930436X
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