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Exosomal miR-212-5p promotes tendon repair via targeting FOXO1 to activate PP1A/YAP1 signaling

Abstract Tendon injury, resulting from repetitive strain or acute trauma, often leads to pain, reduced mobility, and impaired healing due to the limited regenerative capacity of tendon tissue. Adipose-derived stem cells (ADSCs) exosomes show therapeutic promise, though their mechanisms are unclear....

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Principais autores: Kefeng Lin, Xu Hu, Jin Yan, Renzhi Gao, Shishui Lin, Shiguo Zhou
Formato: Artigo
Idioma:Inglês
Publicado: Nature Portfolio 2025-12-01
Series:Communications Biology
Acceso en liña:https://doi.org/10.1038/s42003-025-09210-5
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