Transgene and Chemical Transdifferentiation of Somatic Cells for Rapid and Efficient Neurological Disease Cell Models

For neurological diseases, molecular and cellular research relies on the use of model systems to investigate disease processes and test potential therapeutics. The last decade has witnessed an increase in the number of studies using induced pluripotent stem cells to generate disease relevant cell ty...

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Detalhes bibliográficos

Principais autores:	Neville Ng, Michelle Newbery, Simon Maksour, Mirella Dottori, Ronald Sluyter, Lezanne Ooi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2022-05-01
coleção:	Frontiers in Cellular Neuroscience
Assuntos:	transdifferentiation reprogramming differentiation neurodegeneration transcription factors aging
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fncel.2022.858432/full
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