Intestinal subepithelial myofibroblasts in inflammatory bowel disease: fibroblast heterogeneity, fibrosis, and therapeutic targeting

Intestinal fibrosis remains one of the most challenging complications of inflammatory bowel disease (IBD), frequently leading to bowel strictures, impaired intestinal function, and surgical intervention. Among the stromal cell populations involved in intestinal remodeling, intestinal subepithelial m...

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Автори:	Fang Li, Chao Xu, Jun Chen, Teng Lei, Xigui Tian, Yuanling Zhang, Guoqing Chen
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Frontiers Media S.A. 2026-06-01
Серія:	Frontiers in Medicine
Предмети:	antifibrotic therapy immune–stromal crosstalk inflammatory bowel disease intestinal fibrosis intestinal subepithelial myofibroblasts
Онлайн доступ:	https://www.frontiersin.org/articles/10.3389/fmed.2026.1808431/full
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