Detection of volume loss in hippocampal layers in Alzheimer's disease using 7 T MRI: A feasibility study

In Alzheimer's disease (AD), the hippocampus is an early site of tau pathology and neurodegeneration. Histological studies have shown that lesions are not uniformly distributed within the hippocampus. Moreover, alterations of different hippocampal layers may reflect distinct pathological processes....

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Detalhes bibliográficos

Principais autores:	Claire Boutet, Marie Chupin, Stéphane Lehéricy, Linda Marrakchi-Kacem, Stéphane Epelbaum, Cyril Poupon, Christopher Wiggins, Alexandre Vignaud, Dominique Hasboun, Bénédicte Defontaines, Olivier Hanon, Bruno Dubois, Marie Sarazin, Lucie Hertz-Pannier, Olivier Colliot
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2014-01-01
coleção:	NeuroImage: Clinical
Assuntos:	Alzheimer's disease Human 7 T MRI Hippocampus Hippocampal layers Segmentation Volumetry
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S221315821400103X
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