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cAMP Signaling Enhances HIV-1 Long Terminal Repeat (LTR)-directed Transcription and Viral Replication in Bone Marrow Progenitor Cells

CD34 + hematopoietic progenitor cells have been shown to be susceptible to HIV-1 infection, possibly due to a low-level expression of CXCR4, a coreceptor for HIV-1 entry. Given these observations, we have explored the impact of forskolin on cell surface expression of CXCR4 in a cell line model (TF-1...

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Principais autores: Anupam Banerjee, Luna Li, Vanessa Pirrone, Fred C Krebs, Brian Wigdahl, Michael R Nonnemacher
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publishing 2017-03-01
Serier:Clinical Medicine Insights: Pathology
Online adgang:https://doi.org/10.1177/1179555717694535
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