High-throughput quantitation of amino acids and acylcarnitine in cerebrospinal fluid: identification of PCNSL biomarkers and potential metabolic messengers

Background: Due to the poor prognosis and rising occurrence, there is a crucial need to improve the diagnosis of Primary Central Nervous System Lymphoma (PCNSL), which is a rare type of non-Hodgkin’s lymphoma. This study utilized targeted metabolomics of cerebrospinal fluid (CSF) to identify biomark...

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Autors principals:	Jingjing Ma, Kun Chen, Yun Ding, Xiao Li, Qiming Tang, Bo Jin, Ruben Y. Luo, Sheeno Thyparambil, Zhi Han, C. James Chou, Ashlee Zhou, James Schilling, Zhiguang Lin, Yan Ma, Qing Li, Mengxue Zhang, Karl G. Sylvester, Seema Nagpal, Doff B. McElhinney, Xuefeng B. Ling, Bobin Chen
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2023-10-01
Col·lecció:	Frontiers in Molecular Biosciences
Matèries:	PCNSL cerebrospinal fluid amino acid acylcarnitine UHPLC-MS/MS
Accés en línia:	https://www.frontiersin.org/articles/10.3389/fmolb.2023.1257079/full
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