Dual leucine zipper kinase is required for mechanical allodynia and microgliosis after nerve injury

Neuropathic pain resulting from nerve injury can become persistent and difficult to treat but the molecular signaling responsible for its development remains poorly described. Here, we identify the neuronal stress sensor dual leucine zipper kinase (DLK; Map3k12) as a key molecule controlling the mal...

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Autors principals:	Josette J Wlaschin, Jacob M Gluski, Eileen Nguyen, Hanna Silberberg, James H Thompson, Alexander T Chesler, Claire E Le Pichon
Format:	Artigo
Idioma:	Inglês
Publicat:	eLife Sciences Publications Ltd 2018-07-01
Col·lecció:	eLife
Matèries:	pain microglia somatosensation mechanical allodynia neuropathic kinase
Accés en línia:	https://elifesciences.org/articles/33910
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