Transcriptomic and phenotype analysis revealed the role of rpoS in stress resistance and virulence of a novel ST3355 ESBL-producing hypervirulent Klebsiella pneumoniae isolate

IntroductionAn extended-spectrum beta-lactamase (ESBL)-hypervirulent Klebsiella pneumoniae (HvKP) strain HKE9 was isolated from the blood in an outpatient.MethodsThe effect of the global regulatory factor RpoS on antimicrobial resistance, pathogenicity, and environmental adaptability was elucidated....

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Главные авторы:	Yi Zhou, Yue Cheng, Tianyou Ma, Jun Wang, Shaoru Li, Jingdan Wang, Lei Han, Xinyao Hou, Xinxin Ma, Sijin Jiang, Pu Li, Jia Lv, Bei Han, Rong Da
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Frontiers Media S.A. 2023-10-01
Серии:	Frontiers in Cellular and Infection Microbiology
Предметы:	hypervirulent Klebsiella pneumoniae ESBLs pathogenomic rpoS virulence environmental stress and disinfectants tolerance
Online-ссылка:	https://www.frontiersin.org/articles/10.3389/fcimb.2023.1259472/full
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