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Propofol Inhibits Glioma Stem Cell Growth and Migration and Their Interaction with Microglia via BDNF-AS and Extracellular Vesicles

Glioblastoma (GBM) is the most common and aggressive primary brain tumor. GBM contains a small subpopulation of glioma stem cells (GSCs) that are implicated in treatment resistance, tumor infiltration, and recurrence, and are thereby considered important therapeutic targets. Recent clinical studies...

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Principais autores: Rephael Nizar, Simona Cazacu, Cunli Xiang, Matan Krasner, Efrat Barbiro-Michaely, Doron Gerber, Jonathan Schwartz, Iris Fried, Shira Yuval, Aharon Brodie, Gila Kazimirsky, Naama Amos, Ron Unger, Stephen Brown, Lisa Rogers, Donald H. Penning, Chaya Brodie
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-07-01
Serier:Cells
Fag:
glioblastoma
glioma stem cells
propofol
BDNF-AS
extracellular vesicles
microglia
Online adgang:https://www.mdpi.com/2073-4409/12/15/1921
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