The hypoferremic response to acute inflammation is maintained in thalassemia mice even under parenteral iron loading
Background Hepcidin controls iron homeostasis by inducing the degradation of the iron efflux protein, ferroportin (FPN1), and subsequently reducing serum iron levels. Hepcidin expression is influenced by multiple factors, including iron stores, ineffective erythropoiesis, and inflammation. However,...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
PeerJ Inc.
2021-04-01
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| Series: | PeerJ |
| Assuntos: | |
| Acceso en liña: | https://peerj.com/articles/11367.pdf |
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