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AP-1 Recruits SMAP-1/SMAPs to the trans-Golgi Network to Promote Sorting in Polarized Epithelia

Coordinated AP-1 and clathrin coat assembly mediate secretory sorting on the trans-Golgi network (TGN) during conventional secretion. Here we found that SMAP-1/SMAPs deficiency caused the apical protein ERM-1 to accumulate on the basolateral side of the TGN. In contrast, the basolateral protein SLCF...

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Wedi'i Gadw mewn:
Prif Awduron: Shimin Wang, Longfeng Yao, Wenjuan Zhang, Zihang Cheng, Can Hu, Hang Liu, Yanling Yan, Anbing Shi
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2021-11-01
Cyfres:Frontiers in Cell and Developmental Biology
Pynciau:
C. elegans
polarized sorting
SMAP-1/SMAPs
AP-1
clathrin
intestinal epithelia
Mynediad Ar-lein:https://www.frontiersin.org/articles/10.3389/fcell.2021.774401/full
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