Systematic identification and characterization of compounds with reliable activity against multiple target proteins from different classes

Polypharmacology provides a basis for the treatment of diseases originating from perturbed target and pathway networks. It depends on the use of compounds with suitable multi-target activity and pharmacological effects resulting from multi-target engagement. In addition to their central role for pol...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Sanjana Srinivasan, Jürgen Bajorath
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2024-01-01
Serie:	Results in Chemistry
Soggetti:	Multi-target compounds Polypharmacology Structural relationships Protein classes Unrelated targets Compound-based target relationships
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2211715624000729
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!