Epigenetic modulation reveals differentiation state specificity of oncogene addiction
Epigenetic mechanisms associated with the differentiation state of cancer cells and their heterogeneity influence tumor responses to oncogene-targeted therapies. In this study, the authors perform an epigenetic compound screen and single-cell analysis in BRAF-mutant melanoma cells to identify compou...
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| Hoofdauteurs: | , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Portfolio
2021-03-01
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| Reeks: | Nature Communications |
| Online toegang: | https://doi.org/10.1038/s41467-021-21784-2 |
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