Impact of metformin on intervertebral disc degeneration in patients with diabetes: a prospective cohort study from the UK biobank

Abstract Objective Intervertebral disc degeneration (IDD) is a major contributor to low back pain and disability. Emerging evidence suggests that type 2 diabetes mellitus (T2DM) accelerates IDD progression, while metformin, a first-line treatment for T2DM, may offer protective effects. This study ai...

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主要な著者:	Jianan Chen, Nianchun Liao, Bo Gao, Tongzhou Liang, Wenjun Hu, Zaoqiang Zhang, Wangim Choi, Huihong Shi, Song Liu, Yanbo Chen, Youxi Lin, Zhihuai Deng, Xianjian Qiu, Dongsheng Huang, Wenjie Gao
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2025-12-01
シリーズ:	Diabetology & Metabolic Syndrome
主題:	Metformin Intervertebral disc degeneration T2DM UK biobank
オンライン･アクセス:	https://doi.org/10.1186/s13098-025-02050-7
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