Pharmacogenetics of tenofovir and emtricitabine penetration into cerebrospinal fluid

Background: Blood-cerebrospinal fluid (CSF) barrier transporters affect the influx and efflux of drugs. The antiretrovirals tenofovir and emtricitabine may be substrates of blood-brain barrier (BBB) and blood-CSF barrier transporters, but data are limited regarding the pharmacogenetics and pharmacok...

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主要な著者:	Eric H. Decloedt, Phumla Z. Sinxadi, Lubbe Wiesner, John A. Joska, David W. Haas, Gary Maartens
フォーマット:	Artigo
言語:	Inglês
出版事項:	AOSIS 2021-04-01
シリーズ:	Southern African Journal of HIV Medicine
主題:	pharmacokinetics pharmacogenetics tenofovir emtricitabine cerebrospinal fluid
オンライン･アクセス:	https://sajhivmed.org.za/index.php/hivmed/article/view/1206
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