Mitochondrial heteroplasmy improves risk prediction for myeloid neoplasms
Abstract Clonal hematopoiesis of indeterminate potential is the primary pathogenic risk factor for myeloid neoplasms, while heteroplasmy (mutations in a subset of cellular mitochondrial DNA) is another marker of clonal expansion associated with hematological malignancies. We explore how these two ma...
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| Główni autorzy: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Nature Portfolio
2024-11-01
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| Seria: | Nature Communications |
| Dostęp online: | https://doi.org/10.1038/s41467-024-54443-3 |
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