Imipenem in the Rat Brain: A Multidimensional Study on Hippocampal Behavior, GABAergic System, Astrocyte Response, and Neurogenesis

<b>Background:</b> After imipenem was introduced in clinical practice, neurologic adverse effects led to recommendations against its use in patients with neurologic conditions. However, these conclusions were drawn without considering pharmacokinetic variations in such patients. Furthermore, animal...

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Principais autores:	Leonardo Araújo-Andrade, Bárbara Caetano-Mota, Inês Silva, Ana Rogeiro, Pedro Nogueira, Ana Silva, Pedro A. Pereira, Maria Dulce Madeira, Armando Cardoso
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2026-02-01
Series:	Antibiotics
Assuntos:	imipenem hippocampus memory anxiety neurogenesis astrogliosis
Acceso en liña:	https://www.mdpi.com/2079-6382/15/2/218
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