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Multidrug Combinations against SARS-CoV-2 Using GS-441524 or Ivermectin with Molnupiravir and/or Nirmatrelvir in Reconstituted Human Nasal Airway Epithelia

<b>Background.</b> The emergence, global spread, and persistence of SARS-CoV-2 resulted in an unprecedented need for effective antiviral drugs. Throughout the pandemic, various drug development and treatment strategies were adopted, including repurposing of antivirals designed for other viruses alon...

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Main Authors: Denise Siegrist, Hulda R. Jonsdottir, Mendy Bouveret, Bernadett Boda, Samuel Constant, Olivier B. Engler
Format: Artigo
Language:Inglês
Published: MDPI AG 2024-09-01
Series:Pharmaceutics
Subjects:
SARS-CoV-2
antivirals
molnupiravir
nirmatrelvir
GS-441524
ivermectin
Online Access:https://www.mdpi.com/1999-4923/16/10/1262
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