Fetal overgrowth in the Cdkn1c mouse model of Beckwith-Wiedemann syndrome
SUMMARY Mutations in the imprinted CDKN1C gene are associated with the childhood developmental disorder Beckwith-Wiedemann syndrome (BWS). Multiple mouse models with deficiency of Cdkn1c recapitulate some aspects of BWS but do not exhibit overgrowth of the newborn, a cardinal feature of patients wit...
Gespeichert in:
| Hauptverfasser: | , , |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Company of Biologists
2011-11-01
|
| Schriftenreihe: | Disease Models & Mechanisms |
| Online-Zugang: | http://dmm.biologists.org/content/4/6/814 |
| Tags: |
Keine Tags, Fügen Sie das erste Tag hinzu!
|