Identification of DksA as a novel pro-inflammatory mediator of Pseudomonas aeruginosa under conditions mimicking chronic cystic fibrosis lung infection

Chronic infection with Pseudomonas aeruginosa is a major driver of airway inflammation, which plays a central role in the progression of cystic fibrosis (CF) lung disease. During long-term colonization, P. aeruginosa adapts to the CF lung by downregulating virulence factors and adopting a biofilm-as...

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Hlavní autoři:	Merel Wauters, Laura Bollé, Gilles De Meester, Sara Van den Bossche, Lucia Grassi, Delphi Van Haver, Sara Dufour, Simon Devos, Francis Impens, Eva Van Braeckel, Anna K. H. Hirsch, Marvin Whiteley, Xavier Saelens, Aurélie Crabbé
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis Group 2026-12-01
Edice:	Virulence
Témata:	Pseudomonas aeruginosa virulence factors inflammation cystic fibrosis proteomics transcriptomics
On-line přístup:	https://www.tandfonline.com/doi/10.1080/21505594.2026.2670050
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