Epigenetic regulation by WTAPP1 promotes trophoblast dysfunction in gestational diabetes via CNR1/NF-κB activation

Abstract Gestational diabetes mellitus (GDM) poses significant risks to maternal and fetal health, necessitating exploration of novel molecular mechanisms. Clinical data from placental tissues from 33 GDM patients and 30 controls revealed Wilms tumor 1 associated protein (WTAP) pseudogene 1 (WTAPP1)...

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Detalles Bibliográficos

Principais autores:	Na Yang, Yuan Li, Jiefang Zhang, Xianghong Gao, Peng Zhang, Weiling Li
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2025-10-01
Series:	European Journal of Medical Research
Assuntos:	WTAPP1 Gestational diabetes mellitus CNR1 Trophoblast cells M6A
Acceso en liña:	https://doi.org/10.1186/s40001-025-03217-8
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