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Dextran-Coated Iron Oxide Nanoparticles Loaded with 5-Fluorouracil for Drug-Delivery Applications

This study aims to design and test different formulations composed of dextran-coated iron oxide nanoparticles (IONPs) loaded with 5-Fluorouracil (5-FU) with varying nanoparticle:drug ratios on colorectal cancer cells. The stable suspension of IONPs s was synthesized by the adapted co-precipitation m...

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Principais autores: Daniela Predoi, Mihaela Balas, Madalina Andreea Badea, Steluta Carmen Ciobanu, Nicolas Buton, Anca Dinischiotu
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-06-01
Serier:Nanomaterials
Fag:
iron oxide nanoparticles
dextran
5-Fluorouracil
Caco-2 cells
toxicity
drug-delivery system
Online adgang:https://www.mdpi.com/2079-4991/13/12/1811
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