Genome-scale metabolic modelling identifies reactions mediated by SNP-SNP interactions associated with yeast sporulation
Abstract Genome-scale metabolic models (GEMs) are powerful tools used to understand the functional effects of genetic variants. However, the impact of single nucleotide polymorphisms (SNPs) in transcription factors and their interactions on metabolic fluxes remains largely unexplored. Using gene exp...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Portfolio
2025-05-01
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| Серии: | npj Systems Biology and Applications |
| Online-ссылка: | https://doi.org/10.1038/s41540-025-00503-3 |
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